33 Results for "

Cynanchum otophyllum C. K. Schneid.

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "Cynanchum otophyllum C. K. Schneid." in MCE Product Catalog:

1
Caudatin
Caudatin
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1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Category:  

Asclepiadaceae Cynanchum otophyllum Schneid． Plants Cynanchum auriculatum Royle ex Wight Disease Research Fields Cancer Steroids

Target:  

Apoptosis Autophagy Reactive Oxygen Species (ROS) Mitochondrial Metabolism PARP Caspase Bcl-2 Family VEGFR FAK WDR5 p38 MAPK JNK PPAR

Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
Cynandione A
Cynandione A
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Cat. No.: HY-N8249
CAS No.: 168706-29-4
Category:  

Apocynaceae Phenols Polyphenols Plants Cynanchum boudieri H. Lév. & Vaniot

Target:  

nAChR Interleukin Related

Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression .
Caudatin (Standard)
Caudatin (Standard)
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Cat. No.: HY-N1983R
CAS No.: 38395-02-7
Category:  

Asclepiadaceae Cynanchum otophyllum Schneid． Plants Cynanchum auriculatum Royle ex Wight Steroids

Target:  

Reference Standards Apoptosis Autophagy Reactive Oxygen Species (ROS) Mitochondrial Metabolism PARP Caspase Bcl-2 Family VEGFR FAK WDR5 p38 MAPK JNK PPAR

Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease .
Cynatratoside A
Cynatratoside A
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Cat. No.: HY-N3672
CAS No.: 97399-96-7
Category:  

Cardiacglycosides Asclepiadaceae Cynanchum paniculatum (Bunge) Kitagawa Plants Steroids

Target:  

Others

Cynatratoside A, an oligoglycoside, is a nature product that could be isolated from the roots of Cynanchum paniculatum .
Cynanester A
Cynanester A
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Cat. No.: HY-125545
CAS No.: 143502-52-7
Category:  

Terpenoids Euphorbiaceae Cnidoscolus vitifolius (Mill.) Pohl Plants Pentacyclic Triterpenoids

Target:  

Others

Cynanester A is a active product that can be isolated from Cynanchum chinense R. Br. .
Qingyangshengenin A
Qingyangshengenin A
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Cat. No.: HY-N0581
CAS No.: 106644-33-1
Category:  

Monophenols Asclepiadaceae Phenols Cynanchum otophyllum Schneid． Plants Steroids

Target:  

Others

Qingyangshengenin A, a C-21 steroidal glycoside isolated from the roots of Cynanchum otophyllum Schneid, has antiepileptic activity .
Otophylloside L
Otophylloside L
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Cat. No.: HY-N13318
CAS No.: 1015447-52-5
Category:  

Asclepiadaceae Cynanchum otophyllum Schneid． Plants Steroids

Target:  

Others

Otophylloside L is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside L can be used in epilepsy research .
Otophylloside J
Otophylloside J
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Cat. No.: HY-N13315
CAS No.: 1015447-50-3
Category:  

Asclepiadaceae Cynanchum otophyllum Schneid． Plants Steroids

Target:  

Others

Otophylloside J is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside J can be used in epilepsy research .
Otophylloside H
Otophylloside H
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Cat. No.: HY-N13317
CAS No.: 1015447-48-9
Category:  

Asclepiadaceae Cynanchum otophyllum Schneid． Plants Steroids

Target:  

Others

Otophylloside H is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside H can be used in epilepsy research .
Glaucogenin C mono-D-thevetoside
Glaucogenin C mono-D-thevetoside
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Cat. No.: HY-N3946
CAS No.: 849201-84-9
Synonyms: Glaucogenin C O-β-D-thevetopyranoside
Category:  

Apocynaceae Plants Vincetoxicum stauntonii (Decne.) C. Y. Wu et D. Z. Li Steroids

Target:  

Others

Glaucogenin C mono-D-thevetoside can be isolated from the roots of Cynanchum stauntonii .
Cynatratoside D
Cynatratoside D
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Cat. No.: HY-N12373
CAS No.: 97399-99-0
Category:  

Apocynaceae Plants Vincetoxicum atratum (Bunge) Morren et Decne. Saccharides Monosaccharides

Target:  

Others

Cynatratoside D is a oligoglycoside isolated from the root of Cynanchum atratum Bunge (Asclepiadaceae) .
Glaucogenin C 3-O-α-L-cymaropyranosyl-(1→4)–β-D-digitoxopyranosyl-(1→4)-β-D-canaropyranoside
Glaucogenin C 3-O-α-L-cymaropyranosyl-(1→4)–β-D-digitoxopyranosyl-(1→4)-β-D-canaropyranoside
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Cat. No.: HY-N12816
CAS No.: 1021362-93-5
Category:  

Apocynaceae Plants Vincetoxicum stauntonii (Decne.) C. Y. Wu et D. Z. Li Saccharides Monosaccharides

Target:  

Others

Glaucogenin C 3-O-α-L-cymaropyranosyl-(1→4)–β-D-digitoxopyranosyl-(1→4)-β-D-Canaropyranoside is a steroidal glycoside and can be isolated from Cynanchum stauntonii .
Cynanoside J
Cynanoside J
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Cat. No.: HY-N12720
CAS No.: 1800029-53-1
Category:  

Apocynaceae Cardiacglycosides Plants Vincetoxicum atratum (Bunge) Morren et Decne. Steroids

Target:  

Others

Cynanoside J is a C21 steroidal glycosides that can be obtained from Cynanchum taihangense. The IC50 values of Cynanoside J for HL-60, THP1, and Caco2 are 6.38, 5.82, and 6.76 μM, respectively. Cynanoside J can be used in cancer research .
Otophylloside P
Otophylloside P
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Cat. No.: HY-N18008
CAS No.: 1326583-11-2
Category:  

Apocynaceae Cynanchum otophyllum C. K. Schneid. Plants Steroids

Target:  

Others

Otophylloside P is a pregnane glycosid. Otophylloside P can be isolated from the roots of Cynanchum otophyllum .
Caudatin 3-O-β-D-glucopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside
Caudatin 3-O-β-D-glucopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside
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Cat. No.: HY-N18393
CAS No.: 88797-64-2
Category:  

Apocynaceae Tetracyclic Triterpenoids Cynanchum otophyllum C. K. Schneid. Terpenoids Plants

Target:  

Others

Caudatin 3-O-β-D-glucopyranosyl-(1→4)-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (compound 6) is a C-21 steroidal glycoside that can be isolated from the roots of Cynanchum otophyllum and Cynanchum caudatum .
Bourjotinolone A
Bourjotinolone A
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Cat. No.: HY-N2956
CAS No.: 6985-35-9
Category:  

Phellodendron chinense Schneid. Triterpenes Terpenoids Rutaceae Plants

Target:  

Others

Bourjotinolone A is a Triterpenoids product that can be isolated from the barks of Phellodendron chinense Schneid. .
5,5'-Dimethoxylariciresinol
5,5'-Dimethoxylariciresinol
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Cat. No.: HY-N2648
CAS No.: 116498-58-9
Category:  

Phellodendron chinense Schneid. Rutaceae Lignans Phenylpropanoids Plants

Target:  

Others

5,5'-Dimethoxylariciresinol is a Lignans product that can be isolated from the barks of Phellodendron chinense Schneid. .
Otophylloside Q
Otophylloside Q
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Cat. No.: HY-N18046
CAS No.: 1326583-13-4
Category:  

Apocynaceae Cynanchum otophyllum C. K. Schneid. Plants Steroids

Target:  

Drug Derivative

Otophylloside Q is a pregnane glycoside (C-21 steroidal glycoside) isolated from the roots of Cynanchum otophyllum. With caudatin (HY-N1983), an anticancer agent, as its aglycone, Otophylloside Q contains a sugar chain composed of cymarose, oleandrose and glucose units .
Stauntoside M
Stauntoside M
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Cat. No.: HY-N12380
CAS No.: 1537167-62-6
Category:  

Apocynaceae Natural Products Plants Vincetoxicum stauntonii (Decne.) C. Y. Wu et D. Z. Li

Target:  

Others

Stauntoside M is a steroidal glycoside that can be isolated from the Roots of Cynanchum stauntonii .
Anti-inflammatory agent 80
Anti-inflammatory agent 80
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Cat. No.: HY-N12817
CAS No.: 2128277-55-2
Category:  

Apocynaceae Cardiacglycosides Vincetoxicum forrestii (Schltr.) C. Y. Wu & D. Z. Li Plants Steroids

Target:  

NO Synthase

Anti-inflammatory agent 80 (Compound 2/2f) is an anti-inflammatory agent and has anti-tumor activity. Anti-inflammatory agent 80 can be isolated fromCynanchum limprichtiiSchltr .
Assay Types